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GHRP-6

$19.99 USD

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GHRP-6 (Growth Hormone-Releasing Peptide-6) is a synthetic hexapeptide and one of the earliest widely studied agonists of the growth hormone secretagogue receptor (GHSR-1a). It directly stimulates pituitary growth hormone (GH) release through a dual mechanism: activating GHSR receptors and enhancing the effect of endogenous growth hormone-releasing hormone (GHRH). This high-purity lyophilized peptide is designed for research in endocrinology, growth metabolism, and animal model applications.

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Product details

Dual Agonist Mechanism: Acts on both GHSR receptors and the hypothalamic-pituitary axis to efficiently stimulate pulsatile GH release
High Bioactivity and Stability: Hexapeptide structure ensures stability and resistance to degradation, suitable for long-term experimental studies
Potent Secretagogue Effect: GH-releasing activity is several times stronger than natural GHRH and is not fully inhibited by somatostatin (SST)
Versatile Research Tool: Beyond GH release, useful for studying GH effects on metabolism, immune modulation, and appetite
Stringent Quality Control: Solid-phase synthesized and purified via HPLC (≥98%), with sequence accuracy verified by mass spectrometry

Mechanism of action

GHRP-6 primarily functions through the following pathways:

Direct activation of pituitary GHSR-1a receptors, stimulating GH synthesis and release
Indirect enhancement of hypothalamic GHRH release and suppression of somatostatin secretion, forming a positive feedback loop
Activation of ghrelin signaling pathways, influencing appetite and energy metabolism
Potential GH-independent modulation of immune function and cytoprotective effects

Usage Guidelines (Research UseOnly):

Reconstitute using sterile saline or a specified buffer.

Store lyophilized powder sealed and protected from light at -20°C or below. After reconstitution, aliquot and freeze to avoid repeated freeze-thaw cycles to maintain peptide stability.

Suitable for in vitro wound healing assays, cell migration/proliferation analyses, or subcutaneous/intramuscular injection studies in animal models.

Specific dosage, frequency, and administration routes should be optimized based on published literature and preliminary experimental results, while strictly adhering to animal research ethical guidelines.

Packaging Instructions

Packaging Note: This product is supplied in a sealed, sterile glass vial without any pre‑printed labels. This design supports institutional compliance protocols and allows researchers to apply custom labels that align with specific experimental protocols, ethical approvals, and local regulations. A separate document containing complete product details (name, batch number, purity, content, COA reference, etc.) is included for label customization and record‑keeping.

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