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PT-141

$39.99 USD

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PT-141 is a synthetic heptapeptide and a cyclic analog of α-melanocyte-stimulating hormone (α-MSH). Unlike similar compounds, it does not act directly on the vascular system but exerts its effects through activation of melanocortin receptors (primarily MC4R and MC3R) in the central nervous system. This high-purity lyophilized peptide is designed for neuroendocrine and behavioral pharmacology research.

size 10mg

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Quantity	Discount	Price
1	0%	$39.99
2 - 5	5%	$37.99
6 - 10	10%	$35.99
11 - 15	15%	$33.99

Product details

High-Purity Synthesis: Solid-phase synthesized and purified via HPLC (≥98%), with structure confirmed by mass spectrometry

Mechanism-Specific: Serves as a tool peptide for studying MC receptor pathways and their central regulatory mechanisms

Research-Ready: Lyophilized form ensures high stability, suitable for animal behavioral studies and neural signaling research

Quality Assured: Manufactured under strict quality control, with Certificate of Analysis (COA) provided

Mechanism of action

PT-141 does not rely on the nitric oxide pathway. After crossing the blood-brain barrier, it primarily binds to melanocortin receptors (especially MC4R) in brain regions such as the hypothalamus, activating downstream cAMP/PKA signaling pathways. This modulates neurotransmitter release (e.g., dopamine), influencing physiological and behavioral processes such as sexual arousal, appetite, and stress responses.

Usage Guidelines (Research UseOnly):

Reconstitute using sterile saline or a specified buffer.

Store lyophilized powder sealed and protected from light at -20°C or below. After reconstitution, aliquot and freeze to avoid repeated freeze-thaw cycles to maintain peptide stability.

Suitable for in vitro wound healing assays, cell migration/proliferation analyses, or subcutaneous/intramuscular injection studies in animal models.

Specific dosage, frequency, and administration routes should be optimized based on published literature and preliminary experimental results, while strictly adhering to animal research ethical guidelines.

Packaging Instructions

Packaging Note: This product is supplied in a sealed, sterile glass vial without any pre‑printed labels. This design supports institutional compliance protocols and allows researchers to apply custom labels that align with specific experimental protocols, ethical approvals, and local regulations. A separate document containing complete product details (name, batch number, purity, content, COA reference, etc.) is included for label customization and record‑keeping.

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