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MOTS-C

$25.99 USD

~~$35.99 USD~~ $25.99 USD

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MOTS-c is a mitochondrial-derived peptide encoded by mitochondrial DNA, consisting of 16 amino acids. Recent studies have highlighted its key role in regulating metabolism, cellular stress responses, and energy homeostasis, making it an important signaling molecule in metabolic and aging research.

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Save up to 15% when you buy more!

Quantity	Discount	Price
1	0%	$25.99
2 - 5	5%	$24.69
6 - 10	10%	$23.39
11 - 15	15%	$22.09

Product details

Metabolic Mechanism Research Tool: Ideal for studying glucose/lipid metabolism, insulin sensitivity, and mitochondrial functionCross-Model Applicability: Validated activity in cell cultures and mouse models
Rigorous Quality Control and Stability
High-purity laboratory-grade material ensures reliable and accurate experimental data, specifically designed for tissue repair and cellular function research to support consistent results.

Stable and Easy-to-Use Formulation

Highly stable formulation, easy to handle and reconstitute under standard laboratory conditions.

Mechanism of action

Nuclear Gene Regulation Pathway

Upon entering the nucleus, MOTS-c activates the AMPK-AKT-FOXO1 pathway to promote glucose uptake and utilization, while enhancing antioxidant capacity via the Nrf2 pathway.

Mitochondrial Function Modulation

Within mitochondria, it helps maintain AMP/ATP balance, promotes fatty acid oxidation, inhibits lipogenesis, and improves metabolic flexibility.

Systemic Metabolic Effects

In animal models, MOTS-c enhances insulin sensitivity, improves exercise endurance, and influences whole-body metabolism by modulating hormones such as FGF21.

Usage Guidelines (Research UseOnly):

Reconstitute using sterile saline or a specified buffer.

Store lyophilized powder sealed and protected from light at -20°C or below. After reconstitution, aliquot and freeze to avoid repeated freeze-thaw cycles to maintain peptide stability.

Suitable for in vitro wound healing assays, cell migration/proliferation analyses, or subcutaneous/intramuscular injection studies in animal models.

Specific dosage, frequency, and administration routes should be optimized based on published literature and preliminary experimental results, while strictly adhering to animal research ethical guidelines.

Packaging Instructions

Packaging Note: This product is supplied in a sealed, sterile glass vial without any pre‑printed labels. This design supports institutional compliance protocols and allows researchers to apply custom labels that align with specific experimental protocols, ethical approvals, and local regulations. A separate document containing complete product details (name, batch number, purity, content, COA reference, etc.) is included for label customization and record‑keeping.

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