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EPITALON（10vials）

$110.90 USD

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EPITALON (commonly known as Epithalon or Epithalone) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) that mimics the natural pineal gland peptide Epithalamin. Research suggests it may modulate telomerase activity and influence gene expression, potentially delaying cellular aging processes. This high-purity lyophilized synthetic peptide is designed for research in aging biology, telomere dynamics, and neuroendocrine regulation.

size 10mg*10vials 50mg*10vials

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Quantity	Discount	Price
1	0%	$110.90
2 - 5	5%	$105.36
6 - 10	10%	$99.81
11 - 15	15%	$94.27

Product details

High-Purity Synthesis: Solid-phase synthesized and purified via HPLC (≥98%), with structure verified by mass spectrometry
Mechanism-Focused Research Tool: Used for studying telomere maintenance, cellular senescence, and pineal-related endocrine pathways
Research-Grade Suitability: Lyophilized form ensures stability for cell models (e.g., progeria cell lines) and aged animal studies
Stringent Quality Control: Certificate of Analysis (COA) provided for batch purity and sterility

Mechanism of action

The exact mechanism of EPITALON remains under investigation. Current studies suggest potential pathways include:

Telomere Length Modulation: May mildly activate telomerase activity, slowing telomere shortening in cultured cells
Gene Expression Regulation: Influences expression of genes related to cell cycle, senescence, and DNA repair (e.g., p16, p53, Bcl-2)
Antioxidant & Cytoprotective Effects: May enhance cellular antioxidant defenses, reducing oxidative stress damage
Neuroendocrine Modulation: Mimics pineal polypeptide functions, potentially affecting rhythmic secretion of hormones like melatonin

Usage Guidelines (Research UseOnly):

Reconstitution Method: Reconstitution with sterile physiological saline or pH buffer is recommended. Avoid using solvents containing strong oxidizing agents or protease contaminants.
Experimental Procedure: Depending on the research design, the product can be administered to animal models via intravenous, intraperitoneal, or subcutaneous routes. Refer to relevant literature to determine the appropriate dosage and administration protocol.
Storage Conditions: The lyophilized powder should be stored protected from light at -20℃ or below. After reconstitution, it is recommended to aliquot and store at -80℃, avoiding repeated freeze-thaw cycles.
Precautions: This product is for research use only and is not for human consumption. Handling should comply with laboratory biosafety guidelines and animal experiment ethical guidelines.

Packaging Instructions

Packaging Note: This product is supplied in a sealed, sterile glass vial without any pre‑printed labels. This design supports institutional compliance protocols and allows researchers to apply custom labels that align with specific experimental protocols, ethical approvals, and local regulations. A separate document containing complete product details (name, batch number, purity, content, COA reference, etc.) is included for label customization and record‑keeping.

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