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CJC-1295 without DAC

$19.99 USD

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CJC-1295 (without DAC) is a synthetic growth hormone-releasing hormone (GHRH) analogue consisting of 29 amino acids. It selectively activates pituitary GHRH receptors to stimulate pulsatile release of endogenous growth hormone (GH), without disrupting basal hormone secretion rhythms. This high-purity lyophilized peptide is designed for research in endocrinology, growth metabolism, and aging mechanisms.

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Quantity	Discount	Price
1	0%	$19.99
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Product details

High-Purity Synthesis: Solid-phase synthesized and purified via HPLC (≥98%), with sequence verified by mass spectrometry (MS)

Mechanism-Specific: Functions as a GHRH receptor agonist for studying pulsatile GH secretion and downstream IGF-1 signaling pathways

Research-Grade Stability: Lyophilized form ensures long-term storage stability; reconstituted solution maintains bioactivity for in vivo animal studies

Quality Documentation: Certificate of Analysis (COA) provided for batch purity and sterility testing

Mechanism of action

CJC-1295 (without DAC) binds with high affinity to GHRH receptors on anterior pituitary cells, activating the cAMP/PKA signaling pathway and inducing pulsatile GH secretion from somatotrophs. With a short half-life (approximately 30 minutes), it does not cause continuous GH stimulation, thereby closely mimicking natural pulsatile secretion patterns. This makes it particularly suitable for investigating how GH pulse frequency and amplitude regulate metabolism, growth, and repair processes.

Usage Guidelines (Research UseOnly):

Reconstitution: Reconstitute with sterile saline or a pH-balanced buffer (e.g., acetic acid buffer); gently vortex to avoid foaming

Administration: Typical animal research doses range from 50–200 μg/kg, administered via subcutaneous or intraperitoneal injection; preliminary dose testing is recommended

Storage: Store lyophilized powder at ≤ -20°C protected from light; after reconstitution, aliquot and store at -80°C to avoid freeze-thaw cycles

Important Notes: For research use only. Not for human use. Always follow laboratory biosafety protocols and animal ethics guidelines.

Packaging Instructions

Packaging Note: This product is supplied in a sealed, sterile glass vial without any pre‑printed labels. This design supports institutional compliance protocols and allows researchers to apply custom labels that align with specific experimental protocols, ethical approvals, and local regulations. A separate document containing complete product details (name, batch number, purity, content, COA reference, etc.) is included for label customization and record‑keeping.

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