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CJC1295 with DAC

$25.99 USD

~~$39.99 USD~~ $25.99 USD

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CJC-1295 (with DAC) is a modified growth hormone-releasing hormone (GHRH) analogue. Its structure incorporates a Drug Affinity Complex (DAC) technology, typically involving a lysine-linked serum albumin-binding moiety. This modification dramatically extends its plasma half-life from minutes to approximately 7-10 days, enabling sustained and stable stimulation of pituitary-derived endogenous growth hormone (GH) release. This high-purity lyophilised peptide is designed for endocrine, regenerative medicine, and chronic disease model research requiring prolonged GH elevation.

size 2mg 5mg

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Quantity	Discount	Price
1	0%	$25.99
2 - 5	5%	$24.69
6 - 10	10%	$23.39
11 - 15	15%	$22.09

Product details

Prolonged-Release Technology: DAC modification facilitates reversible binding to serum albumin, significantly extending half-life and enabling days-long GH stimulation.

High-Purity Synthesis: Solid-phase synthesised and purified via HPLC (≥98%), with structure and modification verified by mass spectrometry (MS).

Specific Research Utility: Ideal for animal studies requiring sustained, stable increases in GH levels, providing a mechanistic contrast to short-acting versions (without DAC).

Comprehensive QC: Supplied with Certificate of Analysis (COA) detailing purity, modification rate, and sterility.

Mechanism of action

Receptor activation: Specifically binds to pituitary GHRH receptors (GHRH-R)

Sustained stimulation: DAC modification prolongs activity, promoting continuous GH secretion from pituitary cells

Cascade activation: GH stimulates hepatic IGF-1 synthesis, activating downstream growth and metabolic pathways

Preserved feedback: Does not disrupt natural GH secretion rhythm or negative feedback mechanisms

Usage Guidelines (Research UseOnly):

Reconstitution: Reconstitute with a sterile pH-buffered solution (e.g., bacteriostatic water with 0.6% acetic acid) to enhance stability. Gently vortex; avoid vigorous shaking.Administration:Dosage: A common single-dose range in animal studies is 30–100 μg/kg (optimisation based on model and duration is required).Route: Typically administered via subcutaneous injection for slow release.Frequency: Due to its long-acting profile, once- or twice-weekly dosing is often sufficient to maintain stable GH levels, making it ideal for long-term studies.Storage:Lyophilized Powder: Store at ≤ -20°C, protected from light, for optimal long-term stability.|Reconstituted Solution: Aliquot immediately and store at -80°C. Avoid repeated freeze-thaw cycles to preserve activity.Critical Notes:Research Use Only: Not for human or clinical use.Experimental Design: Account for its onset, plateau, and washout periods due to its prolonged action.Compliance: All research must adhere to institutional animal ethics and biosafety guidelines.

Packaging Instructions

Packaging Note: This product is supplied in a sealed, sterile glass vial without any pre‑printed labels. This design supports institutional compliance protocols and allows researchers to apply custom labels that align with specific experimental protocols, ethical approvals, and local regulations. A separate document containing complete product details (name, batch number, purity, content, COA reference, etc.) is included for label customization and record‑keeping.

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