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AOD9604

AOD9604

Regular price $35.99 USD
Regular price $45.99 USD Sale price $35.99 USD
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AOD9604 is a synthetic peptide fragment derived from a specific sequence of human growth hormone (HGH), corresponding to amino acids 176-191 at the C-terminus of the molecule. Scientific literature confirms that this region of HGH is involved in the regulation of lipid metabolism, independent of the hormone's growth-promoting activity. AOD9604 was developed to isolate and study this metabolic domain while avoiding the activation of pathways traditionally associated with growth hormone receptor stimulation or insulin-like growth factor 1 (IGF-1) regulation.

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Product details

AOD9604 is a synthetic peptide fragment derived from a specific sequence of human growth hormone (HGH), corresponding to amino acids 176-191 at the C-terminus of the molecule. Scientific literature confirms that this region of HGH is involved in the regulation of lipid metabolism, independent of the hormone's growth-promoting activity. AOD9604 was developed to isolate and study this metabolic domain while avoiding the activation of pathways traditionally associated with growth hormone receptor stimulation or insulin-like growth factor 1 (IGF-1) regulation.

Mechanism of action

Lipolysis Activation: Activates hormone-sensitive lipase (HSL) and enhances β-adrenergic receptor signaling to promote triglyceride breakdown.

Lipogenesis Inhibition: Suppresses fatty acid synthase (FAS) activity, reducing de novo fat synthesis.

Metabolic Rate Modulation: May influence energy expenditure via hypothalamic feeding centers or peripheral thermogenesis.

Receptor Pathways: Studies suggest its effects may be partially mediated through specific subtypes of growth hormone receptor (GHR) or non-canonical signaling pathways

Usage Guidelines (Research UseOnly):

It is recommended to reconstitute using sterile saline or the specified buffer.
Store lyophilized powder sealed and protected from light at -20°C or below. After reconstitution, aliquot and freeze to avoid repeated freeze-thaw cycles to maintain peptide stability.
Common routes: Subcutaneous or intraperitoneal injection.
Specific dosage, frequency, and administration routes should be optimized based on published literature and preliminary experimental results, while strictly adhering to animal research ethical guidelines.

Packaging Instructions

Packaging Note: This product is supplied in a sealed, sterile glass vial without any pre‑printed labels. This design supports institutional compliance protocols and allows researchers to apply custom labels that align with specific experimental protocols, ethical approvals, and local regulations. A separate document containing complete product details (name, batch number, purity, content, COA reference, etc.) is included for label customization and record‑keeping.

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AOD9604