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MK-677

MK-677

Regular price $19.99 USD
Regular price Sale price $19.99 USD
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MK-677 (also known as Ibutamoren) is an orally active growth hormone secretagogue receptor agonist that promotes the secretion of growth hormone (GH) and insulin-like growth factor-1 (IGF-1) by mimicking the action of ghrelin. This product is a high-purity synthetic compound specifically designed for research purposes related to the endocrine system, metabolic mechanisms, and musculoskeletal aging.

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1 0% $19.99
2 - 5 5% $18.99
6 - 10 10% $17.99
11 - 15 15% $16.99
Product details

High-Targeting Research Tool:

This high-purity synthetic peptide is manufactured using pharmaceutical-grade processes, offering exceptional stability and solubility.

Stable Lyophilized Form:

Presented in a lyophilized form with stable chemical properties, making it suitable for long-term storage. It exhibits excellent solubility in aqueous solutions and physiological buffers, facilitating easy reconstitution and preparation under laboratory conditions, ensuring operational convenience and reproducibility.

Clear Mechanism and Research Pathway:

Its well-defined mechanism of action provides a clear and reliable pathway for related scientific investigations.

Mechanism of action

MK-677 binds to growth hormone secretagogue receptors in the hypothalamus and pituitary, mimicking endogenous ghrelin signaling. It activates Gq/11 protein-coupled pathways, enhancing sensitivity to growth hormone-releasing hormone and reducing somatostatin inhibition, thereby promoting pituitary growth hormone secretion. Its action is independent of growth hormone-releasing hormone and maintains physiological pulsatile release patterns.

Usage Guidelines (Research UseOnly):

Reconstitution is recommended using sterile saline or a designated buffer.

Lyophilized powder should be stored sealed and protected from light at -20°C or below. After reconstitution, aliquot and freeze to avoid repeated freeze-thaw cycles, thereby maintaining peptide stability.

Suitable for in vitro applications such as cell scratch assays, cell migration/proliferation analysis, or subcutaneous/muscular injection studies in animal models.

Specific dosage, frequency, and administration routes should be optimized based on published literature and preliminary experimental results, while strictly adhering to animal research ethical guidelines.

Packaging Instructions

Packaging Note: This product is supplied in a sealed, sterile glass vial without any pre‑printed labels. This design supports institutional compliance protocols and allows researchers to apply custom labels that align with specific experimental protocols, ethical approvals, and local regulations. A separate document containing complete product details (name, batch number, purity, content, COA reference, etc.) is included for label customization and record‑keeping.

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99%+ Purity Guaranteed

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Rigorous Testing

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MK-677